BDNF Antibody

• Background:

  BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this protein is reduced in both Alzheimer's and Huntington disease patients. This protein may play a role in the regulation of stress response and in the biology of mood disorders.

• NCBI Gene ID:

  627

• Swiss Prot:

  P23560

• Accession Number:

  P23560

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human BDNF.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  28 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  BDNF

• NCBI Official Name:

  Brain-derived neurotrophic factor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Jiang, H., Clin. Chim. Acta 400 (1-2), 3-7 (2009)

• Background Reference 02:

  Liu, L., Psychiatr. Genet. 18 (6), 267-274 (2008)

• Background Reference 03:

  Dmitrzak-Weglarz, M., Pharmacogenomics (11), 1595-1603 (2008)

• Other Product Names:

  Brain-derived neurotrophic factor, BDNF, Abrineurin, BDNF

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  114900

• Physical Properties:

  Liquid