BDNF Recombinant Protein

• Background:

  Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75) . BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.

• NCBI Gene ID:

  627

• Swiss Prot:

  P23560

• Accession Number:

  P23560

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Growth Factors, Neuroscience, Obesity, Signal Transduction, Stem Cell

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  27 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Brain-derived neurotrophic factor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Brain-Derived Neurotrophic Factor, BDNF, Abrineurin

• Species:

  Human

• Protein ID:

  578877726

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3