MAP3K9 Antibody

CAT: 0223-63-311Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-311Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K) . MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
NCBI Gene ID
4293
Swiss Prot
P80192
Accession Number
P80192
Host
Rabbit
Reactivity
Human
Immunogen
This MAP3K9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-189 amino acids from the N-terminal region of human MAP3K9.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
122 kDa
Fragment
Rabbit Ig
Symbol
MAP3K9
NCBI Official Name
Mitogen-activated protein kinase kinase kinase 9
NCBI Organism
Homo sapiens
Background Reference 01
Dorow, D.S., et al., Eur. J. Biochem. 213 (2) :701-710 (1993) .
Other Product Names
Mitogen-activated protein kinase kinase kinase 9, Mixed lineage kinase 1, MAP3K9, MLK1, PRKE1
Tested Applications
WB, IHC-P
Protein ID
116242625
Physical Properties
Liquid

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