MAP2K7 Antibody

• Background:

  The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  5609

• Swiss Prot:

  O14733

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MAP2K7 (NP_660186.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology, Innate Immunity, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 52kDa

• Fragment:

  IgG

• Symbol:

  MAP2K7

• Positive Control 2:

  HL-60

• Positive Control 3:

  Jurkat

• Positive Control 4:

  PC-3

• Positive Control 5:

  K-562

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Mitogen-activated protein kinase kinase 7

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PRKMK7, JNKK2, MKK7, MAP2K7, MP2K7

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid