COPS3 Antibody

• Background:

  COPS3 possesses kinase activity that phosphorylates regulators involved in signal transduction. This protein phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation.

• NCBI Gene ID:

  8533

• Swiss Prot:

  Q9UNS2

• Accession Number:

  Q9UNS2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This COPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-130 amino acids from the Central region of human COPS3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  COPS3

• NCBI Official Name:

  COP9 signalosome complex subunit 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Henriksen J., Aagesen T.H., Maelandsmo G.M., .Oncogene 22:5358-5361 (2003)

• Background Reference 02:

  Potocki L., Chen K.-S., Lupski J.R.Genomics 57:180-182 (1999)

• Background Reference 03:

  Bech-Otschir D., Kraft R., Huang X., EMBO J. 20:1630-1639 (2001)

• Other Product Names:

  COP9 signalosome complex subunit 3, SGN3, Signalosome subunit 3, JAB1-containing signalosome subunit 3, COPS3, CSN3

• Tested Applications:

  WB

• Protein ID:

  55976621

• Physical Properties:

  Liquid