COPS6 Antibody

CAT: 0223-22-676Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-22-676Size:100 µL
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Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
NCBI Gene ID
10980
Swiss Prot
Q7L5N1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 58-327 of human COPS6 (NP_006824.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 36kDa
Fragment
IgG
Symbol
COPS6
Positive Control 2
Jurkat
Positive Control 3
Mouse heart
Positive Control 4
Mouse brain
Positive Control 5
Mouse liver
Positive Control 6
Rat liver
NCBI Official Name
COP9 signalosome subunit 6
NCBI Organism
Homo sapiens
Other Product Names
CSN6, MOV34-34KD, COP9 signalosome complex subunit 6, COP9 constitutive photomorphogenic homolog subunit 6, H_NH0506M12.12, JAB1-containing signalosome subunit 6, MOV34 homolog, 34 kD, SGN6, hVIP, vpr-interacting protein
Tested Applications
WB, IF
Physical Properties
Liquid

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