CDC25C Antibody

• Background:

  CDC25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest.

• NCBI Gene ID:

  995

• Swiss Prot:

  P30307

• Accession Number:

  P30307

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CDC25C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-142 amino acids from the Central region of human CDC25C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  53 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CDC25C

• NCBI Official Name:

  M-phase inducer phosphatase 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Varmeh, S., Mol. Cancer Ther. (12), 3789-3799 (2008)

• Background Reference 02:

  Long, J.M., Cell Cycle (19), 3062-3073 (2008)

• Background Reference 03:

  Bonnet, J., Cell Cycle (13), 1991-1998 (2008)

• Other Product Names:

  M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C

• Tested Applications:

  WB

• Protein ID:

  116242631

• Physical Properties:

  Liquid