Lefty Antibody

• Background:

  LEFTB is a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products.

• NCBI Gene ID:

  10637

• Swiss Prot:

  O75610

• Accession Number:

  O75610

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Lefty (LEFTB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-314 amino acids from the C-terminal region of human Lefty (LEFTB) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  41 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  LEFTY1

• NCBI Official Name:

  Left-right determination factor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kosaki K., Am. J. Hum. Genet. 64:712-721 (1999)

• Background Reference 02:

  Dvash, T., Stem Cells 25 (2), 465-472 (2007)

• Background Reference 03:

  Besser, D., J. Biol. Chem. 279 (43), 45076-45084 (2004)

• Other Product Names:

  Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B, LEFTY1, LEFTB, LEFTYB

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid