LEFTY2 Antibody

• Background :

  This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants.

• NCBI Gene ID :

  7044

• Swiss Prot :

  O00292

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 57-366 of human LEFTY2 (NP_003231.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Signal Transduction, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  LO2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 41kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  LEFTY2

• Positive Control 2 :

  Mouse heart

• Positive Control 3 :

  Rat liver

• NCBI Official Name :

  Left-right determination factor 2

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  LEFTY2, EBAF, LEFTA, LEFTYA, MGC46222, TGFB4

• Tested Applications :

  WB

• Physical Properties :

  Liquid