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LEFTY2 Antibody

CAT: 0223-29-698Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-698Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.
NCBI Gene ID
7044
Swiss Prot
O00292
Accession Number
NP_003231
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LEFTY2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction, Growth Factors
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
RPMI 8826 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LEFTY2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
40 kDa
Applications Notes
LEFTY2 antibody can be used for detection of LEFTY2 by ELISA at 1:312500. LEFTY2 antibody can be used for detection of LEFTY2 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
LEFTY2
NCBI Official Name
Left-right determination factor 2
NCBI Organism
Homo sapiens
Background Reference 01
Cornet, P.B., (2005) J. Clin. Endocrinol. Metab. 90 (2), 1001-1011.
Other Product Names
LEFTY2, EBAF, LEFTA, LEFTYA, MGC46222, TGFB4
Tested Applications
ELISA, WB
Protein ID
27436881
Physical Properties
Liquid

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