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MAPK1 Antibody

CAT: 0223-62-760Size: 400 µLDry Ice: NoHazardous: No
CAT#: 62-760Size: 400 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
NCBI Gene ID
5594
Swiss Prot
P28482
Accession Number
P28482
Host
Rabbit
Reactivity
Human
Immunogen
This MAPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human MAPK1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Xenopus, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
MAPK1
NCBI Official Name
Mitogen-activated protein kinase 1
NCBI Organism
Homo sapiens
Background Reference 01
Munshi, H.G., et al., J. Biol. Chem. 279 (37) :39042-39050 (2004) .
Background Reference 02
Mukherjee, S., et al., Infect. Immun. 72 (9) :5274-5282 (2004) .
Background Reference 03
Lou, Y., et al., Biochem. Biophys. Res. Commun. 321 (2) :495-501 (2004) .
Background Reference 04
Mitsushima, M., et al., J. Biol. Chem. 279 (33) :34570-34577 (2004) .
Other Product Names
Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, MAPK1, ERK2, PRKM1, PRKM2
Tested Applications
WB, IHC-P, Flow
Protein ID
119554
Physical Properties
Liquid

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