DIO1 Antibody

CAT: 0223-62-559Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-559Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3) . It also degrades both hormones by inner ring deiodination (IRD) .
NCBI Gene ID
1733
Swiss Prot
P49895
Accession Number
P49895
Host
Rabbit
Reactivity
Human
Immunogen
This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 amino acids from the N-terminal region of human DIO1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DIO1
NCBI Official Name
Type I iodothyronine deiodinase
NCBI Organism
Homo sapiens
Background Reference 01
Landa, I., et.al., PLoS Genet. (9), E1000637 (2009)
Other Product Names
Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5'-deiodinase, DIO1, ITDI1, TXDI1
Tested Applications
WB
Protein ID
182702125
Physical Properties
Liquid

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