PTP4A2 Antibody

• Background :

  PTP4A2 belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity.

• NCBI Gene ID :

  8073

• Swiss Prot :

  Q12974

• Accession Number :

  Q12974

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PTP4A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-59 amino acids from the Central region of human PTP4A2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  19 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  PTP4A2

• NCBI Official Name :

  Protein tyrosine phosphatase type IVA 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Ewing, R.M., et.al., Mol. Syst. Biol. 3, 89 (2007)

• Other Product Names :

  Protein tyrosine phosphatase type IVA 2, HU-PP-1, OV-1, PTP (CAAXII), Protein-tyrosine phosphatase 4a2, Protein-tyrosine phosphatase of regenerating liver 2, PRL-2, PTP4A2, PRL2, PTPCAAX2

• Tested Applications :

  WB, IHC-P, IF, Flow

• Protein ID :

  68566159

• Physical Properties :

  Liquid