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PTP4A1 Antibody

CAT: 0223-58-807Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-807Size:400 µL
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Background
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq].
NCBI Gene ID
7803
Swiss Prot
Q93096
Accession Number
Q93096
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PTP4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human PTP4A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PTP4A1
NCBI Official Name
Protein tyrosine phosphatase type IVA 1
NCBI Organism
Homo sapiens
Background Reference 01
Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :
Background Reference 02
Skinner, A.L., et al. Biochemistry 48 (20) :4262-4272 (2009)
Background Reference 03
Luo, Y., et al. Biochemistry 48 (8) :1838-1846 (2009)
Background Reference 04
Min, S.H., et al. Oncogene 28 (4) :545-554 (2009)
Other Product Names
Protein tyrosine phosphatase type IVA 1, PTP (CAAXI), Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1, PRL-1, PTP4A1, PRL1, PTPCAAX1
Tested Applications
WB
Protein ID
68566217
Physical Properties
Liquid

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