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PTPRN2 Antibody

CAT: 0223-15-722Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-15-722Size:100 µL
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Background
This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
5799
Swiss Prot
Q92932
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-242 of human PTPRN2 (NP_570858.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 111kDa
Fragment
IgG
Symbol
PTPRN2
Positive Control 2
SGC-7901
Positive Control 3
Mouse pancreas
Positive Control 4
Rat pancreas
NCBI Official Name
Receptor-type tyrosine-protein phosphatase N2
NCBI Organism
Homo sapiens
Other Product Names
Receptor-type tyrosine-protein phosphatase N2, R-PTP-N2, Islet cell autoantigen-related protein, IAR, ICAAR, Phogrin, PTPRN2, KIAA0387
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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