ABCC1 Antibody

• Background :

  ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC gene are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.

• NCBI Gene ID :

  4363

• Swiss Prot :

  P33527

• Accession Number :

  P33527

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ABCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1247-1275 amino acids from the C-terminal region of human ABCC1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Obesity, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  172 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ABCC1

• NCBI Official Name :

  Multidrug resistance-associated protein 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Siedlinski, M., Pharmacogenet. Genomics 19 (9), 675-684 (2009)

• Other Product Names :

  Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Leukotriene C (4) transporter, LTC4 transporter, ABCC1, MRP, MRP1

• Tested Applications :

  WB, Flow

• Protein ID :

  296439301

• Physical Properties :

  Liquid