ABCC10 Antibody

• Background:

  The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White) . This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  89845

• Swiss Prot:

  Q5T3U5

• Accession Number:

  Q5T3U5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-793 amino acids from the Central region of human ABCC10.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  162 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ABCC10

• NCBI Official Name:

  Multidrug resistance-associated protein 7

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kuang, Y.H., et al. Biochem. Pharmacol. 79 (2) :154-161 (2010)

• Background Reference 02:

  Saito, A., et al. J. Hum. Genet. 54 (6) :317-323 (2009)

• Background Reference 03:

  Zhou, Y., et al. Biochem. Pharmacol. 77 (6) :993-1001 (2009)

• Background Reference 04:

  Hopper-Borge, E., et al. Cancer Res. 69 (1) :178-184 (2009)

• Other Product Names:

  Multidrug resistance-associated protein 7, ATP-binding cassette sub-family C member 10, ABCC10, MRP7, SIMRP7

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  74756298

• Physical Properties:

  Liquid