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ABCC12 Antibody

CAT: 0223-56-913Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-913Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
NCBI Gene ID
94160
Swiss Prot
Q96J65
Accession Number
Q96J65
Host
Rabbit
Reactivity
Mouse
Immunogen
This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the Central region of human ABCC12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
152 kDa
Fragment
Rabbit Ig
Symbol
ABCC12
NCBI Official Name
Multidrug resistance-associated protein 9
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Haimeur, A., et al. Curr. Drug Metab. 5 (1) :21-53 (2004)
Background Reference 03
Bera, T.K., et al. Proc. Natl. Acad. Sci. U.S.A. 99 (10) :6997-7002 (2002)
Background Reference 04
Yabuuchi, H., et al. Biochem. Biophys. Res. Commun. 288 (4) :933-939 (2001)
Other Product Names
Multidrug resistance-associated protein 9, ATP-binding cassette sub-family C member 12, ABCC12, MRP9
Tested Applications
WB, IHC-P
Protein ID
161788999
Physical Properties
Liquid

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