ABCC12 Antibody

• Background :

  This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.

• NCBI Gene ID :

  94160

• Swiss Prot :

  Q96J65

• Accession Number :

  Q96J65

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the Central region of human ABCC12.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  152 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ABCC12

• NCBI Official Name :

  Multidrug resistance-associated protein 9

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02 :

  Haimeur, A., et al. Curr. Drug Metab. 5 (1) :21-53 (2004)

• Background Reference 03 :

  Bera, T.K., et al. Proc. Natl. Acad. Sci. U.S.A. 99 (10) :6997-7002 (2002)

• Background Reference 04 :

  Yabuuchi, H., et al. Biochem. Biophys. Res. Commun. 288 (4) :933-939 (2001)

• Other Product Names :

  Multidrug resistance-associated protein 9, ATP-binding cassette sub-family C member 12, ABCC12, MRP9

• Tested Applications :

  WB, IHC-P

• Protein ID :

  161788999

• Physical Properties :

  Liquid