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ABCC4 Antibody

CAT: 0223-62-908Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-908Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions.
NCBI Gene ID
10257
Swiss Prot
O15439
Accession Number
O15439
Host
Rabbit
Reactivity
Human
Immunogen
This ABCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1117-1145 amino acids from the C-terminal region of human ABCC4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
150 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ABCC4
NCBI Official Name
Multidrug resistance-associated protein 4
NCBI Organism
Homo sapiens
Background Reference 01
Lee K., Belinsky M.G., Bell D.W.Cancer Res. 58:2741-2747 (1998)
Background Reference 02
Adachi M., Sampath J., Lan L.B.J. Biol. Chem. 277:38998-39004 (2002)
Background Reference 03
Kool M., de Haas M., Scheffer G.L.Cancer Res. 57:3537-3547 (1997)
Background Reference 04
Janke D., Mehralivand S., Strand D.Hum. Mutat. 29:659-669 (2008)
Other Product Names
Multidrug resistance-associated protein 4, ATP-binding cassette sub-family C member 4, MRP/cMOAT-related ABC transporter, Multi-specific organic anion transporter B, MOAT-B, ABCC4, MRP4
Tested Applications
WB
Physical Properties
Liquid

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