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CLC4 Antibody

CAT: 0223-62-251Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-251Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders.
NCBI Gene ID
1183
Swiss Prot
P51793
Accession Number
P51793
Host
Rabbit
Reactivity
Human
Immunogen
This CLC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 663-689 amino acids from the C-terminal region of human CLC4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
85 kDa
Fragment
Rabbit Ig
Symbol
CLCN4
NCBI Official Name
H (+) /Cl (-) exchange transporter 4
NCBI Organism
Homo sapiens
Background Reference 01
Wang, T., et al., Gastroenterology 126 (4) :1157-1166 (2004) .
Background Reference 02
Lamb, F.S., et al., J. Mol. Cell. Cardiol. 31 (3) :657-666 (1999) .
Background Reference 03
Dinulos, M.B., et al., Genomics 35 (1) :244-247 (1996) .
Background Reference 04
Schnur, R.E., et al., Hum. Genet. 95 (5) :594-595 (1995) .
Other Product Names
H (+) /Cl (-) exchange transporter 4, Chloride channel protein 4, ClC-4, Chloride transporter ClC-4, CLCN4
Tested Applications
WB, IHC-P, IF
Protein ID
20141247
Physical Properties
Liquid

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