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CLC Antibody

CAT: 0223-57-733Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-733Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.
NCBI Gene ID
1178
Swiss Prot
Q05315
Accession Number
Q05315
Host
Rabbit
Reactivity
Human
Immunogen
This CLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the C-terminal region of human CLC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
16 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CLC
NCBI Official Name
Galectin-10
NCBI Organism
Homo sapiens
Background Reference 01
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 02
Bryborn, M., et al. Allergy 65 (2) :220-228 (2010)
Background Reference 03
De Re, V., et al. Ann. N. Y. Acad. Sci. 1173, 357-364 (2009) :
Background Reference 04
Than, N.G., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (24) :9731-9736 (2009)
Other Product Names
Galectin-10, Gal-10, Charcot-Leyden crystal protein, CLC, Eosinophil lysophospholipase, Lysolecithin acylhydrolase, CLC, LGALS10, LGALS10A
Tested Applications
WB
Protein ID
317373429
Physical Properties
Liquid

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