CLC Antibody

• Background:

  Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

• NCBI Gene ID:

  1178

• Swiss Prot:

  Q05315

• Accession Number:

  Q05315

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the C-terminal region of human CLC.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  16 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CLC

• NCBI Official Name:

  Galectin-10

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 02:

  Bryborn, M., et al. Allergy 65 (2) :220-228 (2010)

• Background Reference 03:

  De Re, V., et al. Ann. N. Y. Acad. Sci. 1173, 357-364 (2009) :

• Background Reference 04:

  Than, N.G., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (24) :9731-9736 (2009)

• Other Product Names:

  Galectin-10, Gal-10, Charcot-Leyden crystal protein, CLC, Eosinophil lysophospholipase, Lysolecithin acylhydrolase, CLC, LGALS10, LGALS10A

• Tested Applications:

  WB

• Protein ID:

  317373429

• Physical Properties:

  Liquid