MCCC1 Antibody

• Background:

  MCCC1 is the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA.

• NCBI Gene ID:

  56922

• Swiss Prot:

  Q96RQ3

• Accession Number:

  Q96RQ3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This MCCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-425 amino acids from the Central region of human MCCC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  80 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MCCC1

• NCBI Official Name:

  Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Holzinger, A., et al. Hum. Mol. Genet. 10 (12) :1299-1306 (2001)

• Background Reference 02:

  Obata, K., et al. Genomics 72 (2) :145-152 (2001)

• Background Reference 03:

  Baumgartner, M.R., et al. J. Clin. Invest. 107 (4) :495-504 (2001)

• Background Reference 04:

  Gallardo, M.E., et al. Am. J. Hum. Genet. 68 (2) :334-346 (2001)

• Other Product Names:

  Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial, MCCase subunit alpha, 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA carboxylase biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha, MCCC1, MCCA

• Tested Applications:

  WB

• Protein ID:

  108861983

• Physical Properties:

  Liquid