MCCC1 Antibody

• Background :

  MCCC1 is the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA.

• NCBI Gene ID :

  56922

• Swiss Prot :

  Q96RQ3

• Accession Number :

  Q96RQ3

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This MCCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-425 amino acids from the Central region of human MCCC1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  80 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  MCCC1

• NCBI Official Name :

  Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Holzinger, A., et al. Hum. Mol. Genet. 10 (12) :1299-1306 (2001)

• Background Reference 02 :

  Obata, K., et al. Genomics 72 (2) :145-152 (2001)

• Background Reference 03 :

  Baumgartner, M.R., et al. J. Clin. Invest. 107 (4) :495-504 (2001)

• Background Reference 04 :

  Gallardo, M.E., et al. Am. J. Hum. Genet. 68 (2) :334-346 (2001)

• Other Product Names :

  Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial, MCCase subunit alpha, 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA carboxylase biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha, MCCC1, MCCA

• Tested Applications :

  WB

• Protein ID :

  108861983

• Physical Properties :

  Liquid