MCCC2 Antibody

• Background:

  This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

• NCBI Gene ID:

  64087

• Swiss Prot:

  Q9HCC0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 284-563 of human MCCC2 (NP_071415.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 61kDa

• Fragment:

  IgG

• Symbol:

  MCCC2

• Positive Control 2:

  HepG2

• Positive Control 3:

  K562

• Positive Control 4:

  U-251MG

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, MCCase subunit beta, 3-methylcrotonyl-CoA carboxylase 2, 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta, MCCC2, MCCB

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid