ASMT Antibody

• Background:

  ASMT belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland.

• NCBI Gene ID:

  438

• Swiss Prot:

  P46597

• Accession Number:

  P46597

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ASMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-241 amino acids from the Central region of human ASMT.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ASMT

• NCBI Official Name:

  Acetylserotonin O-methyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Melke, J., et al. Mol. Psychiatry 13 (1) :90-98 (2008)

• Background Reference 02:

  Toma, C., et al. Mol. Psychiatry 12 (11) :977-979 (2007)

• Background Reference 03:

  Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

• Background Reference 04:

  Itoh, M.T., et al. Horm. Metab. Res. 35 (3) :153-157 (2003)

• Other Product Names:

  Acetylserotonin O-methyltransferase, Hydroxyindole O-methyltransferase, HIOMT, ASMT

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  1170276

• Physical Properties:

  Liquid