CFL1 Antibody

• Background:

  Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.

• NCBI Gene ID:

  1072

• Swiss Prot:

  P23528

• Accession Number:

  P23528

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the Central region of human CFL1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Pig, Rat, Chicken, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  19 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CFL1

• NCBI Official Name:

  Cofilin-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Fazal, F., et.al., J. Biol. Chem. 284 (31), 21047-21056 (2009)

• Other Product Names:

  Cofilin-1, 18 kDa phosphoprotein, p18, Cofilin, non-muscle isoform, CFL1, CFL

• Tested Applications:

  WB, Flow

• Protein ID:

  116848

• Physical Properties:

  Liquid