CFL2 Antibody

• Background :

  This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  1073

• Swiss Prot :

  Q9Y281

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human CFL2 (NP_068733.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  A-549

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 18kDa

• Fragment :

  IgG

• Symbol :

  CFL2

• Positive Control 2 :

  HeLa

• Positive Control 3 :

  Raji

• Positive Control 4 :

  NCI-H460

• Positive Control 5 :

  Mouse heart

• Positive Control 6 :

  Mouse skeletal muscle

• NCBI Official Name :

  Cofilin 2 (muscle)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Cofilin 2, NEM7, CFL2, HGNC:1875, cofilin 2 (muscle)

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid