MGAT1 Antibody

CAT: 0223-61-379Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-379Size:400 µL
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Background
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. MGAT1 (UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I) is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis.
NCBI Gene ID
4245
Swiss Prot
P26572
Accession Number
P26572
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MGAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human MGAT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
MGAT1
NCBI Official Name
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Tan, J., et al., Eur. J. Biochem. 231 (2) :317-328 (1995) .
Background Reference 02
Kumar, R., et al., Glycobiology 2 (4) :383-393 (1992) .
Background Reference 03
Hull, E., et al., Biochem. Biophys. Res. Commun. 176 (2) :608-615 (1991) .
Background Reference 04
Kumar, R., et al., Proc. Natl. Acad. Sci. U.S.A. 87 (24) :9948-9952 (1990) .
Other Product Names
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, GNT-I, GlcNAc-T I, MGAT1, GGNT1, GLCT1, GLYT1, MGAT
Tested Applications
WB, IHC-P
Protein ID
311033399
Physical Properties
Liquid

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