MGAT2 Antibody

CAT: 0223-31-348Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-31-348Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MGAT2 is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in its gene may lead to carbohydrate-deficient glycoprotein syndrome, type II.The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. Two transcript variants encoding the same protein have been identified for this gene.
NCBI Gene ID
4247
Swiss Prot
Q10469
Accession Number
NP_002399
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MGAT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MGAT2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
51 kDa
Applications Notes
MGAT2 antibody can be used for detection of MGAT2 by ELISA at 1:62500. MGAT2 antibody can be used for detection of MGAT2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MGAT2
NCBI Official Name
Mannosyl (alpha-1,6-) -glycoprotein beta-1,2-N-acetylglucosaminyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Otsuki, T., (2005) DNA Res. 12 (2), 117-126.
Other Product Names
MGAT2, CDGS2, GLCNACTII, GNT-II, GNT2, CDG2A
Tested Applications
ELISA, WB, IHC
Protein ID
4505163
Physical Properties
Liquid

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