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MGAT2 Antibody

CAT: 0223-61-381Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-381Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MGAT2 (UDP-N-acetylglucosamine:alpha-6-D-mannoside-beta-1, 2-N-acetylglucosaminyltransferase II) is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in MGAT2 may lead to carbohydrate-deficient glycoprotein syndrome, type II.
NCBI Gene ID
4247
Swiss Prot
Q10469
Accession Number
Q10469
Host
Rabbit
Reactivity
Human
Immunogen
This MGAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human MGAT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Symbol
MGAT2
NCBI Official Name
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Yen, C.L., et al., J. Biol. Chem. 278 (20) :18532-18537 (2003) . Chen, S.H., et al., Glycoconj. J. 15 (3) :301-308 (1998) . Tan, J., et al., Am. J. Hum. Genet. 59 (4) :810-817 (1996) . Tan, J., et al., Eur. J. Biochem. 231 (2) :317-328 (1995) . D'Agostaro, G.A., et al., J. Biol. Chem. 270 (25) :15211-15221 (1995) .
Other Product Names
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, Beta-1,2-N-acetylglucosaminyltransferase II, GlcNAc-T II, GNT-II, Mannoside acetylglucosaminyltransferase 2, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II, MGAT2
Tested Applications
WB, Flow
Protein ID
1708004
Physical Properties
Liquid

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