Products for Research Use Only
RegisterLogin

TIGIT Antibody

CAT: 0223-61-342Size: 200 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-61-342Size:200 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
NCBI Gene ID
201633
Swiss Prot
Q495A1
Accession Number
Q495A1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TIGIT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-142 amino acids from human TIGIT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
TIGIT
NCBI Official Name
T-cell immunoreceptor with Ig and ITIM domains
NCBI Organism
Homo sapiens
Background Reference 01
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Background Reference 02
Bechtel S., et al.BMC Genomics 8:399-399 (2007) .
Background Reference 03
Yu X., et al.Nat. Immunol. 10:48-57 (2009) .
Background Reference 04
Stengel K.F., et al.Proc. Natl. Acad. Sci. U.S.A. 109:5399-5404 (2012) .
Other Product Names
T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3, TIGIT, VSIG9, VSTM3
Tested Applications
WB
Protein ID
121943253
Physical Properties
Liquid

Related Products

CatalogName
92-691TIGIT Recombinant Protein
97-037TIGIT Recombinant Protein
96-955TIGIT Recombinant Protein
97-026TIGIT Recombinant Protein
96-798TIGIT Recombinant Protein
97-025TIGIT Recombinant Protein
92-456TIGIT Recombinant Protein
96-799TIGIT Recombinant Protein
97-048TIGIT Recombinant Protein
SD8800TIGIT Detection Set

Alternative Products

CatalogName
MBS9217285-01TIGIT Antibody

Popular Products