DNM2 Antibody

• Background :

  Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity) . Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis.

• NCBI Gene ID :

  1785

• Swiss Prot :

  P50570

• Accession Number :

  P50570

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This DNM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 213-247 amino acids from human DNM2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  98 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  DNM2

• NCBI Official Name :

  Dynamin-2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Diatloff-Zito C., et al.Gene 163:301-306 (1995) .

• Background Reference 02 :

  Ota T., et al.Nat. Genet. 36:40-45 (2004) .

• Background Reference 03 :

  Grimwood J., et al.Nature 428:529-535 (2004) .

• Background Reference 04 :

  Okamoto P.M., et al.J. Biol. Chem. 276:48458-48465 (2001) .

• Other Product Names :

  Dynamin-2, 3.6.5.5, DNM2, DYN2

• Tested Applications :

  WB, Flow

• Protein ID :

  47117856

• Physical Properties :

  Liquid