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SPTLC3 Antibody

CAT: 0223-61-312Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-312Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Serine palmitoyltransferase (SPT) . The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, while the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.
NCBI Gene ID
55304
Swiss Prot
Q9NUV7
Accession Number
Q9NUV7
Host
Rabbit
Reactivity
Human
Immunogen
This SPTLC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 503-545 amino acids from human SPTLC3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
SPTLC3
NCBI Official Name
Serine palmitoyltransferase 3
NCBI Organism
Homo sapiens
Background Reference 01
Hornemann T., et al.J. Biol. Chem. 281:37275-37281 (2006) .
Background Reference 02
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Background Reference 03
Deloukas P., et al.Nature 414:865-871 (2001) .
Background Reference 04
Han G., et al.Proc. Natl. Acad. Sci. U.S.A. 106:8186-8191 (2009) .
Other Product Names
Serine palmitoyltransferase 3, 2.3.1.50, Long chain base biosynthesis protein 2b, LCB2b, Long chain base biosynthesis protein 3, LCB 3, Serine-palmitoyl-CoA transferase 3, SPT 3, SPTLC3, C20orf38, SPTLC2L
Tested Applications
WB
Protein ID
158931158
Physical Properties
Liquid

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