NT5C Antibody

• Background:

  Dephosphorylates the 5' and 2' (3') -phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.

• NCBI Gene ID:

  30833

• Swiss Prot:

  Q8TCD5

• Accession Number:

  Q8TCD5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NT5C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 164-195 amino acids from human NT5C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  23 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  NT5C

• NCBI Official Name:

  5' (3') -deoxyribonucleotidase, cytosolic type

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rampazzo C., et al.J. Biol. Chem. 275:5409-5415 (2000) .

• Background Reference 02:

  Ota T., et al.Nat. Genet. 36:40-45 (2004) .

• Background Reference 03:

  Zody M.C., et al.Nature 440:1045-1049 (2006) .

• Background Reference 04:

  Rampazzo C., et al.Gene 294:109-117 (2002) .

• Other Product Names:

  5' (3') -deoxyribonucleotidase, cytosolic type, 3.1.3.-, Cytosolic 5',3'-pyrimidine nucleotidase, Deoxy-5'-nucleotidase 1, dNT-1, NT5C, DNT1, UMPH2

• Tested Applications:

  WB

• Protein ID:

  38258193

• Physical Properties:

  Liquid