NT5M Antibody

• Background:

  Dephosphorylates specifically the 5' and 2' (3') - phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.

• NCBI Gene ID:

  56953

• Swiss Prot:

  Q9NPB1

• Accession Number:

  Q9NPB1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NT5M antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 59-90 amino acids from the Central region of human NT5M.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  NT5M

• NCBI Official Name:

  5' (3') -deoxyribonucleotidase, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rampazzo C., et al.Proc. Natl. Acad. Sci. U.S.A. 97:8239-8244 (2000) .

• Background Reference 02:

  Rinaldo-Matthis A., et al.Nat. Struct. Biol. 9:779-787 (2002) .

• Other Product Names:

  5' (3') -deoxyribonucleotidase, mitochondrial, 5',3'-nucleotidase, mitochondrial, 3.1.3.-, Deoxy-5'-nucleotidase 2, dNT-2, NT5M, DNT2

• Tested Applications:

  WB

• Protein ID:

  38258255

• Physical Properties:

  Liquid