GDF9 Antibody

• Background:

  GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.

• NCBI Gene ID:

  2661

• Swiss Prot:

  O60383

• Accession Number:

  O60383

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GDF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human GDF9.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GDF9

• NCBI Official Name:

  Growth/differentiation factor 9

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Liao, W.X., et al., J. Biol. Chem. 278 (6) :3713-3719 (2003) .

• Background Reference 02:

  Vitt, U.A., et al., Biol. Reprod. 67 (2) :473-480 (2002) .

• Background Reference 03:

  Aaltonen, J., et al., J. Clin. Endocrinol. Metab. 84 (8) :2744-2750 (1999) .

• Background Reference 04:

  Dong, J., et al., Nature 383 (6600) :531-535 (1996) .

• Other Product Names:

  Growth/differentiation factor 9, GDF-9, GDF9

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid