GDF3 Antibody

• Background:

  GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.

• NCBI Gene ID:

  9573

• Swiss Prot:

  Q9NR23

• Accession Number:

  Q9NR23

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GDF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-197 amino acids from the Central region of human GDF3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  41 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GDF3

• NCBI Official Name:

  Growth/differentiation factor 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) .

• Background Reference 02:

  Ducy, P., et al., Kidney Int. 57 (6) :2207-2214 (2000) .

• Background Reference 03:

  Caricasole, A.A., et al., Oncogene 16 (1) :95-103 (1998) .

• Other Product Names:

  Growth/differentiation factor 3, GDF-3, GDF3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  46397885

• Physical Properties:

  Liquid