GDF2 Antibody

• Background:

  The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia.

• NCBI Gene ID:

  2658

• Swiss Prot:

  Q9UK05

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 320-429 of human GDF2 (NP_057288.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology

• Purification:

  Affinity purification

• Positive Control:

  Mouse pancreas

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 47kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  GDF2

• Positive Control 2:

  Mouse skeletal muscle

• Positive Control 3:

  Rat skeletal muscle

• NCBI Official Name:

  Growth differentiation factor 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GDF2, growth differentiation factor 2, BMP-9, BMP9, bone morphogenetic protein 9

• Tested Applications:

  WB

• Physical Properties:

  Liquid