USP21 Antibody

• Background:

  USP21 is a ubiquitin-specific protease, an enzyme that removes ubiquitin from ubiquitinated proteins. The encoded protein belongs to the C19 peptidase family, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. This protein has been reported to be capable of removing NEDD8 from NEDD8 conjugates.

• NCBI Gene ID:

  27005

• Swiss Prot:

  Q9UK80

• Accession Number:

  Q9UK80

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This USP21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-256 amino acids from the Central region of human USP21.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  63 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  USP21

• NCBI Official Name:

  Ubiquitin carboxyl-terminal hydrolase 21

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Puente, X.S., et al., Nat. Rev. Genet. 4 (7) :544-558 (2003) .

• Background Reference 02:

  Gong, L., et al., J. Biol. Chem. 275 (19) :14212-14216 (2000) .

• Background Reference 03:

  Hillier, L.D., et al., Genome Res. 6 (9) :807-828 (1996) .

• Background Reference 04:

  Smith, T.S., et al., Biochim. Biophys. Acta 1490 (1-2), 184-188 (2000) .

• Other Product Names:

  Ubiquitin carboxyl-terminal hydrolase 21, Deubiquitinating enzyme 21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21, USP21, USP23

• Tested Applications:

  WB

• Protein ID:

  10720334

• Physical Properties:

  Liquid