USP12 Antibody

• Background:

  USP12is a deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.

• NCBI Gene ID:

  219333

• Swiss Prot:

  O75317

• Accession Number:

  O75317

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This USP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the Central region of human USP12.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Xenopus, Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  USP12

• NCBI Official Name:

  Ubiquitin carboxyl-terminal hydrolase 12

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kee, Y., et al. J. Biol. Chem. 285 (15) :11252-11257 (2010)

• Background Reference 02:

  Asano, K., et al. Nat. Genet. 41 (12) :1325-1329 (2009)

• Background Reference 03:

  Cohn, M.A., et al. J. Biol. Chem. 284 (8) :5343-5351 (2009)

• Background Reference 04:

  Dunham, A., et al. Nature 428 (6982) :522-528 (2004)

• Other Product Names:

  Ubiquitin carboxyl-terminal hydrolase 12, Deubiquitinating enzyme 12, Ubiquitin thioesterase 12, Ubiquitin-hydrolyzing enzyme 1, Ubiquitin-specific-processing protease 12, USP12, UBH1, USP12L1

• Tested Applications:

  WB

• Physical Properties:

  Liquid