USP22 Antibody

CAT: 0223-27-157Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-27-157Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.
NCBI Gene ID
23326
Swiss Prot
Q9UPT9
Accession Number
NP_056091
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human USP22.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store USP22 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
60 kDa
Applications Notes
USP22 antibody can be used for detection of USP22 by ELISA at 1:312500. USP22 antibody can be used for detection of USP22 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
USP22
NCBI Official Name
Ubiquitin specific peptidase 22
NCBI Organism
Homo sapiens
Background Reference 01
Zhang, X.Y., (2008) Mol. Cell 29 (1), 102-111.
Other Product Names
USP22, KIAA1063, USP3L
Tested Applications
ELISA, WB
Protein ID
150010639
Physical Properties
Liquid

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