EIF2C2 Antibody

• Background:

  EIF2C2 is a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing.

• NCBI Gene ID:

  239528

• Swiss Prot:

  Q8CJG0

• Accession Number:

  Q8CJG0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This EIF2C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-59 amino acids from the N-terminal region of human EIF2C2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Rabbit, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  97 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  Ago2

• NCBI Official Name:

  Protein argonaute-2 {ECO:0000255|HAMAP-Rule:MF_03031}

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Rivas, F.V., et al., Nat Struct Mol Biol 12 (4) :340-349 (2005) .

• Background Reference 02:

  Liu, J., et al., Science 305 (5689) :1437-1441 (2004) .

• Background Reference 03:

  Nelson, P.T., et al., RNA 10 (3) :387-394 (2004) .

• Background Reference 04:

  Sasaki, T., et al., Genomics 82 (3) :323-330 (2003) .

• Other Product Names:

  Protein argonaute-2 {ECO:0000255|HAMAP-Rule:MF_03031}, Argonaute2 {ECO:0000255|HAMAP-Rule:MF_03031}, mAgo2, 3126n2 {ECO:0000255|HAMAP-Rule:MF_03031}, Argonaute RISC catalytic component 2, Eukaryotic translation initiation factor 2C 2 {ECO:0000255|HAMAP-Rule:MF_03031}, eIF-2C 2 {ECO:0000255|HAMAP-Rule:MF_03031}, eIF2C 2 {ECO:0000255|HAMAP-Rule:MF_03031}, Piwi/argonaute family protein meIF2C2, Protein slicer {ECO:0000255|HAMAP-Rule:MF_03031}, Ago2, Eif2c2, Kiaa4215

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid