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ZMPSTE24 Antibody

CAT: 0223-60-794Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-794Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.
NCBI Gene ID
10269
Swiss Prot
O75844
Accession Number
O75844
Host
Rabbit
Reactivity
Human
Immunogen
This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-433 amino acids from the C-terminal region of human ZMPSTE24.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ZMPSTE24
NCBI Official Name
CAAX prenyl protease 1 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Miner, J.H. Am. J. Med. Genet.152A (8), 2140-2141 (2010) :
Background Reference 03
Smigiel, R., et al. Am. J. Med. Genet.152A (2), 447-452 (2010) :
Background Reference 04
Fontaine-Bisson, B., et al. J. Mol. Med. 88 (2) :193-201 (2010)
Other Product Names
CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24
Tested Applications
WB
Physical Properties
Liquid

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GWB-MQ521HZMPSTE24 Antibody
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CSB-CL026504HUZMPSTE24

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