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HIST2H2AC Antibody

CAT: 0223-60-780Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-780Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.
NCBI Gene ID
8338
Swiss Prot
Q16777
Accession Number
Q16777
Host
Rabbit
Reactivity
Human
Immunogen
This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat, Bovine, Xenopus, Mouse, Chicken, Monkey, Zebrafish, D
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
14 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HIST2H2AC
NCBI Official Name
Histone H2A type 2-C
NCBI Organism
Homo sapiens
Background Reference 01
Ishibashi, T., et al. Biochemistry 48 (22) :5007-5017 (2009)
Background Reference 02
Karaczyn, A.A., et al. Ann. Clin. Lab. Sci. 39 (3) :251-262 (2009)
Background Reference 03
Pinato, S., et al. BMC Mol. Biol. 10, 55 (2009) :
Background Reference 04
Guerrero-Santoro, J., et al. Cancer Res. 68 (13) :5014-5022 (2008)
Other Product Names
Histone H2A type 2-C, Histone H2A-GL101, Histone H2A/q, HIST2H2AC, H2AFQ
Tested Applications
WB
Protein ID
47117890
Physical Properties
Liquid

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