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HIST2H2AA4 Antibody

CAT: 0223-57-382Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-382Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
NCBI Gene ID
7237908337
Swiss Prot
Q6FI13
Accession Number
Q6FI13
Host
Rabbit
Reactivity
Human
Immunogen
This HIST2H2AA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human HIST2H2AA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat, Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
14 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HIST2H2AA3
NCBI Official Name
Histone H2A type 2-A
NCBI Organism
Homo sapiens
Background Reference 01
Braastad, C.D., et al. Gene 342 (1) :35-40 (2004)
Background Reference 02
Marzluff, W.F., et al. Genomics 80 (5) :487-498 (2002)
Background Reference 03
Mannironi, C., et al. DNA Cell Biol. 13 (2) :161-170 (1994)
Background Reference 04
Allen, B.S., et al. Genomics 10 (2) :486-488 (1991)
Other Product Names
Histone H2A type 2-A, Histone H2A2, Histone H2A/o, HIST2H2AA3, H2AFO, HIST2H2AA
Tested Applications
WB
Protein ID
74757558
Physical Properties
Liquid

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