MTHFR Antibody

CAT: 0223-60-733Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-733Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
NCBI Gene ID
4524
Swiss Prot
P42898
Accession Number
P42898
Host
Rabbit
Reactivity
Human
Immunogen
This MTHFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-292 amino acids from the Central region of human MTHFR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MTHFR
NCBI Official Name
Methylenetetrahydrofolate reductase
NCBI Organism
Homo sapiens
Background Reference 01
Singh, K., et al.Postgrad Med 56 (4) :267-269 (2010)
Background Reference 02
Harisha, P.N., et al.Neurosurg Pediatr 6 (4) :364-367 (2010)
Background Reference 03
Wu, H.C., et al. Anticancer Res. 30 (9) :3573-3577 (2010)
Background Reference 04
Magnowski, P., et al. Ginekol. Pol. 81 (7) :506-510 (2010)
Other Product Names
Methylenetetrahydrofolate reductase, MTHFR
Tested Applications
WB
Protein ID
56405339
Physical Properties
Liquid

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