MTHFS Antibody

• Background:

  MTHFS contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.

• NCBI Gene ID:

  10052802110588

• Swiss Prot:

  P49914

• Accession Number:

  P49914

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This MTHFS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-159 amino acids from the C-terminal region of human MTHFS.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  23 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MTHFS

• NCBI Official Name:

  5-formyltetrahydrofolate cyclo-ligase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kelemen, L.E., et al. Cancer Epidemiol. Biomarkers Prev. 19 (7) :1822-1830 (2010)

• Background Reference 02:

  Hazra, A., et al. Cancer Causes Control 21 (3) :331-345 (2010)

• Background Reference 03:

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Background Reference 04:

  Wu, D., et al. Cancer Res. 69 (18) :7294-7301 (2009)

• Other Product Names:

  5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydrofolate synthetase, MTHFS, Methenyl-THF synthetase, MTHFS

• Tested Applications:

  WB

• Physical Properties:

  Liquid