MTHFS Antibody

• Background:

  The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.

• NCBI Gene ID:

  10588

• Swiss Prot:

  P49914

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-203 of human MTHFS (NP_006432.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 23kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  MTHFS

• Positive Control 2:

  A-549

• Positive Control 3:

  HepG2

• Positive Control 4:

  HeLa

• Positive Control 5:

  Jurkat

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  MTHFS, FLJ30410, HsT19268

• Tested Applications:

  WB

• Physical Properties:

  Liquid