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CB1 Antibody

CAT: 0223-60-631Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-631Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq].
NCBI Gene ID
1268
Swiss Prot
P21554
Accession Number
P21554
Host
Rabbit
Reactivity
Human
Immunogen
This CB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids from the Central region of human CB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CNR1
NCBI Official Name
Cannabinoid receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Van Laere, K., et al. J. Nucl. Med. 51 (9) :1413-1417 (2010)
Background Reference 03
Larrinaga, G., et al. Histol. Histopathol. 25 (9) :1133-1138 (2010)
Background Reference 04
Monteleone, P., et al.Clin Psychopharmacol 30 (4) :441-445 (2010)
Other Product Names
Cannabinoid receptor 1, CB-R, CB1, CANN6, CNR1, CNR
Tested Applications
WB
Protein ID
115562
Physical Properties
Liquid

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