EIF4H Antibody

• Background:

  This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.

• NCBI Gene ID:

  7458

• Swiss Prot:

  Q15056

• Accession Number:

  Q15056

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This EIF4H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the Central region of human EIF4H.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  27 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  EIF4H

• NCBI Official Name:

  Eukaryotic translation initiation factor 4H

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Feng, T., et al. Hum. Genet. 128 (3) :269-280 (2010)

• Background Reference 02:

  Zhu, X., et al. Genet. Epidemiol. 34 (2) :171-187 (2010)

• Background Reference 03:

  Mokas, S., et al. Mol. Biol. Cell 20 (11) :2673-2683 (2009)

• Background Reference 04:

  Marintchev, A., et al. Cell 136 (3) :447-460 (2009)

• Other Product Names:

  Eukaryotic translation initiation factor 4H, eIF-4H, Williams-Beuren syndrome chromosomal region 1 protein, EIF4H, KIAA0038, WBSCR1, WSCR1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  18276665

• Physical Properties:

  Liquid